A Systematic Review of Cervical Ganglioneuromas

Objective To perform a systematic review of the literature evaluating clinical characteristics and management cervical ganglioneuromas (CGNs). Data Sources PubMed, Embase, Cochrane Library databases were searched. such as patient demographics, imaging, treatments obtained. Review Methods Pertinent studies downloaded, full text was reviewed by 4 authors (N.P., S.S., C.F., D.T.). Results reported via PRISMA guidelines (Preferred Reporting Items for Systematic Reviews Meta-analyses). Fifty-two with 58 patients identified in literature. Of patients, 22 adults 36 pediatric. The most common location CGN within parapharyngeal space (76%), followed retropharyngeal (19%) paravertebral/prevertebral (7%) spaces. presenting symptoms included nontender mass (29.3%), dysphagia (17.2%), hoarseness (10.3%). Interestingly, average tumor volume postoperative Horner’s syndrome 183 mm3 (n = 21, 47.7%) vs 946 without 23, 52.3%). This represents statistically significant finding (P =. 018). There exists no difference volumes between adult pediatric 645). Conclusion is rare sympathetic nervous system. Management should involve complete surgical excision biopsy. We found that small-volume CGNs are significantly more likely to experience syndrome. independent age therefore be taken into consideration any suspected CGN.